Anticomplementary, anticoagulatory, and serum-protein precipitating activity of sodium polyanetholsulfonate.
نویسندگان
چکیده
Sodium polyanetholsulfonate (SPS) at 7.8 mug/ml completely abolished complement-mediated hemolysis of 1:10 diluted fresh guinea pig and human serum; at least twice as much SPS was required to reduce complement activity in 1:2 diluted human serum. The coagulation of 90 and 20% human blood was inhibited by 250 and 125 mug of SPS per ml, respectively. When added to fresh human serum, SPS precipitated beta 1C-globulin (C3), C4, beta lipoproteins, immunoglobulin IgG, IgM, and IgA, though incompletely.
منابع مشابه
Anticoagulatory, and Serum- Protein Precipitating Activity of Sodium Polyanetholsulfonate
Sodium polyanetholsulfonate (SPS) at 7.8 Ag/ml completely abolished complement-mediated hemolysis of 1:10 diluted fresh guinea pig and human serum; at least twice as much SPS was required to reduce complement activity in 1: 2 diluted human serum. The coagulation of 90 and 20% human blood was inhibited by 250 and 125 Ag of SPS per ml, respectively. When added to fresh human serum, SPS precipitat...
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ورودعنوان ژورنال:
- Applied microbiology
دوره 20 3 شماره
صفحات -
تاریخ انتشار 1970